HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491162Generated: November 1, 2026
HCID 85765608, compound → HCID 132510268, compound
https://huagongshe.com/reaction/1491162
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 85765608 | HCID 85765608 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | 2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine | HCID 134956623 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | P-Xylene | HCID 7809 | — |
| Product | HCID 132510268 | HCID 132510268 | 90% |
Reaction Steps
Ligand 3f: A mixture of ortho- and meta-borylated products (145 mg, 90% yield, ortho/meta + para = >30); ortho-borylated product 4r was obtained by further purification by GPC (132 mg, 82% yield), white solid (mp. 48-50 oC)
Provenance & Evidence
| DOI | 10.1002/anie.201610041 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-eca204d81c644d04b8167d2cb43fb8c3 |
|---|
| Source note | Borylation dataset from Roche |
|---|
