HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491166Generated: November 1, 2026
HCID 155019327, compound → HCID 178503287, compound
https://huagongshe.com/reaction/1491166
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 155019327 | HCID 155019327 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | 2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine | HCID 134956623 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | P-Xylene | HCID 7809 | — |
| Product | HCID 178503287 | HCID 178503287 | 70% |
Reaction Steps
Ligand 3f: A mixture of ortho- and meta-borylated products (112 mg, 70% yield, ortho/meta + para = >30); ortho-borylated product 4t was obtained by further purification by GPC (99 mg, 62% yield), yellow oil;
Provenance & Evidence
| DOI | 10.1002/anie.201610041 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-7144e5080f4f4bccabcc2f4319621e6e |
|---|
| Source note | Borylation dataset from Roche |
|---|
