HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491168Generated: November 1, 2026
HCID 123797079, compound → HCID 178503288, compound
https://huagongshe.com/reaction/1491168
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 123797079 | HCID 123797079 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | 2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine | HCID 134956623 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | P-Xylene | HCID 7809 | — |
| Product | HCID 178503288 | HCID 178503288 | 73% |
Reaction Steps
Ligand 3f: A mixture of ortho- and meta-borylated products (122 mg, 73% yield, ortho/meta + para = >30); ortho-borylated product 4u was obtained by further purification by GPC (102 mg, 61% yield), white solid (mp. 92-94 oC);
Provenance & Evidence
| DOI | 10.1002/anie.201610041 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-33e05e26be524eadb761e501b25b9b13 |
|---|
| Source note | Borylation dataset from Roche |
|---|
