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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491187Generated: October 26, 2026

N-(2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl)benzamide → N-[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

https://huagongshe.com/reaction/1491187

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl)benzamideHCID 86708425—
ReagentBis(pinacolato)diboraneHCID 2733548—
ReagentCID 43835029HCID 43835029—
ReagentMethanesulfonic acid, 1,1,1-trifluoro-, sodium salt (1:1)HCID 45051934—
Catalystpalladium(I) acetateHCID 58759193—
SolventAcetonitrileHCID 6342—
ProductN-[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamideHCID 10155752218%

Reaction Conditions

Temperature80 °C

Provenance & Evidence

DOI10.1021/ja2097095
Source datasetBorylation dataset from Roche
ORD IDord-d4dbc684ee534545b1a6096ff625f8be
Source noteBorylation dataset from Roche