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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491189Generated: October 26, 2026

N-(2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl)benzamide → N-[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

https://huagongshe.com/reaction/1491189

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl)benzamideHCID 86708425—
ReagentBis(pinacolato)diboraneHCID 2733548—
ReagentSodium p-toluenesulfonateHCID 24195884—
Catalystpalladium(I) acetateHCID 58759193—
SolventAcetonitrileHCID 6342—
ProductN-[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamideHCID 10155752212%

Reaction Conditions

Temperature80 °C

Provenance & Evidence

DOI10.1021/ja2097095
Source datasetBorylation dataset from Roche
ORD IDord-a4adefdb73b44ca0b29344ff02229ff9
Source noteBorylation dataset from Roche