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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491202Generated: October 30, 2026

N-(2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl)benzamide → N-[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

https://huagongshe.com/reaction/1491202

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl)benzamideHCID 86708425—
ReagentDibenzylidene acetoneHCID 95417—
ReagentBis(pinacolato)diboraneHCID 2733548—
ReagentSodium p-toluenesulfonateHCID 24195884—
ReagentCID 43835029HCID 43835029—
Catalystpalladium(I) acetateHCID 58759193—
SolventAcetonitrileHCID 6342—
ProductN-[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamideHCID 10155752255%

Reaction Conditions

Temperature80 °C

Provenance & Evidence

DOI10.1021/ja2097095
Source datasetBorylation dataset from Roche
ORD IDord-d67a7e8a97154241a0628218dbca7527
Source noteBorylation dataset from Roche