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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491233Generated: October 31, 2026

N-Boc-4-hydroxyaniline → Tert-butyl (4-hydroxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)phenyl)carbamate

https://huagongshe.com/reaction/1491233

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Boc-4-hydroxyanilineHCID 2756771—
ReagentBis(pinacolato)diboraneHCID 2733548—
Reagent4,4,5,5-Tetramethyl[1,3,2]dioxaborolaneHCID 2734768—
Reagent4,4'-Di-tert-butyl-2,2'-bipyridylHCID 4249187—
CatalystBis(1,5-cyclooctadiene)dimethoxydiiridiumHCID 76001521—
Solventtert-Butyl methyl etherHCID 15413—
ProductTert-butyl (4-hydroxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)phenyl)carbamateHCID 7174293878%

Reaction Conditions

Temperature50 °C

Provenance & Evidence

DOI10.1021/ja303443m
Source datasetBorylation dataset from Roche
ORD IDord-1139608af0de453f8fc0d7e140ea28b2
Source noteBorylation dataset from Roche