1,3-Dimethoxybenzene → 2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

HRID 1491390Notes

Reaction equation

HRID 1491390 reaction equation
COc1cccc(OC)c1>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCc2c(c3c(c4c2CCCC4)CCCC3)C1.CC(=O)OC(C)C.CC1(C)OBOC1(C)C.C[OH2+].C[OH2+].Cc1cnc2c(ccc3c(C)c(C)cnc32)c1C.[Ir].[Ir]>COc1cc(OC)cc(B2OC(C)(C)C(C)(C)O2)c1

Participants

7

Reactant 1

HCID 90251,3-Dimethoxybenzene

Product 1

HCID 162176602-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneYield 27%

Reagents, catalysts & solvents 5

HCID 742653,4,7,8-Tetramethyl-1,10-phenanthrolineReagentHCID 95278DodecahydrotriphenyleneReagentHCID 27347684,4,5,5-Tetramethyl[1,3,2]dioxaborolaneReagentHCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridiumCatalystHCID 7915Isopropyl AcetateSolvent

Conditions

Temperature
80 °C

Sources & evidence

ORD record
ord-9606a0779cb24813b8335dd495cef621
Source dataset
Borylation dataset from Roche

Reaction notes

Loading…