1,3-Dimethoxybenzene → 2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

HRID 1491391Notes

Reaction equation

HRID 1491391 reaction equation
COc1cccc(OC)c1>C1CCc2c(c3c(c4c2CCCC4)CCCC3)C1.CC(=O)OC(C)C.CC1(C)OBOC1(C)C>COc1cc(OC)cc(B2OC(C)(C)C(C)(C)O2)c1

Participants

5

Reactant 1

HCID 90251,3-Dimethoxybenzene

Product 1

HCID 162176602-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneYield 28%

Reagents, catalysts & solvents 3

HCID 95278DodecahydrotriphenyleneReagentHCID 27347684,4,5,5-Tetramethyl[1,3,2]dioxaborolaneReagentHCID 7915Isopropyl AcetateSolvent

Conditions

Temperature
80 °C

Sources & evidence

ORD record
ord-8b3b52361f8a4e5a9a16fe8a85de4d3d
Source dataset
Borylation dataset from Roche

Reaction notes

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