HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491461Generated: November 2, 2026
Benzonitrile, 4-(trifluoromethyl)- → 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzonitrile
https://huagongshe.com/reaction/1491461
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzonitrile, 4-(trifluoromethyl)- | HCID 67995 | — |
| Reagent | 4,4,5,5-Tetramethyl[1,3,2]dioxaborolane | HCID 2734768 | — |
| Reagent | 4,4'-Di-tert-butyl-2,2'-bipyridyl | HCID 4249187 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzonitrile | HCID 56973107 | 68% |
Provenance & Evidence
| DOI | 10.1021/ja0428309 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-6a067bf346cd4496a97749228fc9bcee |
|---|
| Source note | Borylation dataset from Roche |
|---|
