HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491467Generated: October 31, 2026
3,4-Dichlorobenzonitrile → 4,5-Dichloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
https://huagongshe.com/reaction/1491467
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3,4-Dichlorobenzonitrile | HCID 81051 | — |
| Reagent | 4,4,5,5-Tetramethyl[1,3,2]dioxaborolane | HCID 2734768 | — |
| Reagent | 4,4'-Di-tert-butyl-2,2'-bipyridyl | HCID 4249187 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4,5-Dichloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile | HCID 57633872 | 72% |
| Product | 863868-40-0 | HCID 57633898 | 17% |
Provenance & Evidence
| DOI | 10.1021/ja0428309 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-502144bb24ec47d5a8090f4ed0dbd46e |
|---|
| Source note | Borylation dataset from Roche |
|---|