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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491468Generated: November 1, 2026

1,5-Dimethylpyrrole-2-carbonitrile → 1,5-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-2-carbonitrile

https://huagongshe.com/reaction/1491468

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,5-Dimethylpyrrole-2-carbonitrileHCID 91812—
Reagent4,4,5,5-Tetramethyl[1,3,2]dioxaborolaneHCID 2734768—
Reagent4,4'-Di-tert-butyl-2,2'-bipyridylHCID 4249187—
CatalystBis(1,5-cyclooctadiene)dimethoxydiiridiumHCID 76001521—
SolventTetrahydrofuranHCID 8028—
Product1,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-2-carbonitrileHCID 5321716014%
Product1,5-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-2-carbonitrileHCID 5321717166%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1021/ja0428309
Source datasetBorylation dataset from Roche
ORD IDord-86987cba45f54bfdab60c6e33a96a8bd
Source noteBorylation dataset from Roche