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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491472Generated: October 25, 2026

Isoquinoline, 1-(1-naphthalenyl)- → HCID 101547934, compound

https://huagongshe.com/reaction/1491472

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsoquinoline, 1-(1-naphthalenyl)-HCID 3838254—
ReagentBis(pinacolato)diboraneHCID 2733548—
Reagent4,4,5,5-Tetramethyl[1,3,2]dioxaborolaneHCID 2734768—
ReagentN,N-Dibenzyl-N'-(pyridin-2-ylmethylene)hydrazineHCID 67601456—
CatalystHCID 82923HCID 82923—
SolventTetrahydrofuranHCID 8028—
ProductHCID 101547934HCID 10154793478%

Reaction Conditions

Temperature50 °C

Reaction Steps

Following the general procedure, column chromatography (EtOAc/nhexane 1:3) afforded 9a (160 mg, 84 %) as a light yellow solid. Evaporation from EtOAc/n-hexane afforded X-Ray quality crystals.

Provenance & Evidence

DOI10.1002/anie.201104544
Source datasetBorylation dataset from Roche
ORD IDord-dbc1b898cf314bf695e9c9589f09b86f
Source noteBorylation dataset from Roche