Isoquinoline, 1-(1-naphthalenyl)- → HCID 101547934, 화합물

HRID 1491483노트

반응식

HRID 1491483 반응식
c1ccc2c(-c3nccc4ccccc34)cccc2c1>C(=NN(Cc1ccccc1)Cc1ccccc1)c1ccccn1.C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CC1(C)OBOC1(C)C.C[OH2+].C[OH2+].[Ir].[Ir]>CC1(C)OB(c2ccc3ccccc3c2-c2nccc3ccccc23)OC1(C)C

참가 물질

7

반응물 1

HCID 3838254Isoquinoline, 1-(1-naphthalenyl)-

생성물 1

HCID 101547934HCID 101547934, 화합물수율 70%

시약·촉매·용매 5

HCID 2733548Bis(pinacolato)diborane시약HCID 27347684,4,5,5-Tetramethyl[1,3,2]dioxaborolane시약HCID 67601456N,N-Dibenzyl-N'-(pyridin-2-ylmethylene)hydrazine시약HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium촉매HCID 8028Tetrahydrofuran용매

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온도
25 °C

실험 절차

Following the general procedure, column chromatography (EtOAc/nhexane 1:3) afforded 9a (160 mg, 84 %) as a light yellow solid. Evaporation from EtOAc/n-hexane afforded X-Ray quality crystals.

출처 및 근거

ORD 기록
ord-c3244b4454d44270872522925f68de66
출처 데이터셋
Borylation dataset from Roche

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