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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 149149Generated: October 26, 2026

1,2-Dichloroethane → Methyl 4-[(3-hydroxy-1-oxo-1-phenylmethoxypropan-2-yl)amino]-4-oxo-3-[[4-tri(propan-2-yl)silyloxyphenyl]methyl]butanoate

https://huagongshe.com/reaction/149149

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantHydrochloric AcidHCID 313—
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantBenzyl 2-amino-3-hydroxypropanoateHCID 3788223—
ReactantMethyl (+/-)-3-carboxy-4-[4-(triisopropylsilyloxy)phenyl]butanoateHCID 20775649—
ProductMethyl 4-[(3-hydroxy-1-oxo-1-phenylmethoxypropan-2-yl)amino]-4-oxo-3-[[4-tri(propan-2-yl)silyloxyphenyl]methyl]butanoateHCID 22496073—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-566910857c714ced9128f2952a7501c9
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)