Triethylamine → HCID 18953200, compound

Participants

Reaction Steps

9.8 ml of triethylamine was added to a solution of 6.59 of p-hydrazinobenzenesulfonic acid in 30 ml of methanol to obtain a homogeneous solution. Then, to the solution was added 4.49 g of 4-acetyltetrahydropyran and refluxed for 1 hour. The solvent was evaporated under reduced pressure, followed by adding 30 ml of acetic acid and refluxing for 30 hours. Acetic acid was evaporated under reduced pressure and 7.1 g of desired oily product was isolated by silica gel column chromatography.

Provenance & Evidence