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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491554Generated: October 26, 2026

L-Glutamine → 4-Isocyanato-4'-methyldiphenylmethane

https://huagongshe.com/reaction/1491554

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-GlutamineHCID 5961—
ReactantSodium BicarbonateHCID 516892—
ReactantSodium pyruvateHCID 23662274—
ReactantHCID 178431920HCID 178431920—
Product4-Isocyanato-4'-methyldiphenylmethaneHCID 22094277—

Reaction Steps

To the Iscove's Modified Dulbecco's Medium is added sodium bicarbonate (0.6%), Modified Eagles Medium Non-Essential Amino Acid Solution (200 μM), sodium pyruvate (2.0 mM) , L-glutamine (4 mM) and antibiotics as required (in the following experiments Penicillin/Streptomycin (200 U/ml each)).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05371010
Source datasetuspto-grants-1994_12
ORD IDord-0384a42087ec4ff1a1618095b72de211
Source noteuspto-grants-1994_12