Water → HCID 18953326, compound

Participants

Reaction Steps

A mixture of t-butyl 2-cyclopropylcarbonyl-3-(2-methylsulphonyl-3-phenylsulphenylphenyl)-3-oxopropionoate (8.5 g) and para-toluene sulphonic acid (0.25 g) in toluene was heated at reflux for six hours. Water and ethyl acetate were then added and the organic phase was dried over anhydrous sodium sulphate, filtered and evaporated. The residue was crystallised from ether to give 1-cyclopropyl-3-(2-methylsulphonyl-3-phenylsulphenylphenyl)propan-1,3-dione (6.2 g) as a beige powder,

Provenance & Evidence