反应详情

A mixture of methyl 2 -methylsulphonyl-3-phenylsulphenylbenzoate (8.3 g), ethanol (50 ml) and 2N sodium hydroxide (25 ml) was heated at reflux for one hour and then added to water. The inorganic phase was washed with ethyl acetate, acidified with concentrated hydrochloric acid and extracted with ethyl acetate. This organic phase was dried over sodium sulphate, filtered and evaporated giving 7.9 g of 2-methylsulphonyl-3-phenylsulphenylbenzoic acid as a white solid, m.p. 185.4°-186.0° C.

1. temperaturewas heated
2. temperatureat reflux for one hour
3. washThe inorganic phase was washed with ethyl acetate
4. extractionextracted with ethyl acetate
5. dry with materialThis organic phase was dried over sodium sulphate
6. filtrationfiltered
7. customevaporated