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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491598Generated: October 31, 2026

1-(4-Iodophenyl)-4-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octane → 1-[4-(3-Methoxyprop-1-ynyl)phenyl]-4-n-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octane

https://huagongshe.com/reaction/1491598

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Iodophenyl)-4-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octaneHCID 15021959—
Reactant4-t-Butyl-1-[4-(3-methoxyprop-1-ynyl)phenyl]-2,6,7-trioxabicyclo[2,2,2]octaneHCID 15021966—
Product1-[4-(3-Methoxyprop-1-ynyl)phenyl]-4-n-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octaneHCID 15021984—

Reaction Steps

1-[4-(3-Methoxyprop-1-ynyl)phenyl]-4-n-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octane was prepared from 1-(4-iodophenyl)-4-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octane and methyl propargyl ether using the methodology described in Example 3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05371075
Source datasetuspto-grants-1994_12
ORD IDord-e895df1f1ab94697895faa659e82bb9b
Source noteuspto-grants-1994_12