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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491705Generated: November 1, 2026

Purine → HCID 57164858, compound

https://huagongshe.com/reaction/1491705

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPurineHCID 1044—
Reactant(1S)-[(2R)-(2,4-difluorophenyl)-2-oxiranyl]ethanolHCID 10631861—
ProductHCID 57164858HCID 5716485847.7%

Reaction Steps

Using (1S)-1-[(2R)-2-(2,4-difluorophenyl)-2-oxiranyl]ethanol (1.03 g) and purine (500 mg), (2S)-2-(2,4-difluorophenyl)-2-[(1R)-1-(9H-9-purinyl)ethyl]oxirane (600 mg) was obtained by the same way as in Reference Example 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05371100
Source datasetuspto-grants-1994_12
ORD IDord-df3368815ff3472dadae0e741352e0fe
Source noteuspto-grants-1994_12