HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1S)-[(2R)-(2,4-difluorophenyl)-2-oxiranyl]ethanol → HCID 15285746, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1S)-[(2R)-(2,4-difluorophenyl)-2-oxiranyl]ethanol | HCID 10631861 | — |
| Reactant | 4-(4-Methoxyphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one | HCID 13208155 | — |
| Product | HCID 15285746 | HCID 15285746 | 33.7% |
Reaction Steps
In the same manner as in Reference Example 5, starting from 1.73 g of (1S)-1-[(2R)-2-(2,4-difluorophenyl)-2-oxiranyl] ethanol and 1.32 g of 4-(4-methoxyphenyl)-3(2H,4H)-1,2,4-triazolone, 2-[(1R,2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-4-(4-methoxyphenyl)-3(2H,4H)-1,2,4-triazolone (869 mg) was obtained as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05371101 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-a079aac1923644c882cf5fa17e6bb558 |
| Source note | uspto-grants-1994_12 |