HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1S)-[(2R)-(2,4-difluorophenyl)-2-oxiranyl]ethanol → HCID 15285761, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1S)-[(2R)-(2,4-difluorophenyl)-2-oxiranyl]ethanol | HCID 10631861 | — |
| Reactant | 4-(pyridin-4-yl)-4,5-dihydro-1H-1,2,4-triazol-5-one | HCID 19373711 | — |
| Product | HCID 15285761 | HCID 15285761 | 33.8% |
Reaction Steps
In the same manner as in Reference Example 5, starting from 1.42 g of (1S)-1-[(2R)-2-(2,4-difluorophenyl)-2-oxiranyl]ethanol and 0.92 g of 4-(4-pyridyl)-3(2H,4H)-1,2,4-triazolone, 2-[(1R, 2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-4-(4-pyridyl )-3 (2H, 4H)-1,2,4-triazolone(0.66 g) was obtained as colorless prisms.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05371101 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-6593a0f4783f4abab80537c7611e5a51 |
| Source note | uspto-grants-1994_12 |