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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491768Generated: October 31, 2026

(1S)-[(2R)-(2,4-difluorophenyl)-2-oxiranyl]ethanol → HCID 15285773, compound

https://huagongshe.com/reaction/1491768

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1S)-[(2R)-(2,4-difluorophenyl)-2-oxiranyl]ethanolHCID 10631861—
Reactant1-(4-chlorophenyl)-1H-tetrazol-5-olHCID 135532015—
ProductHCID 15285773HCID 1528577360.5%

Reaction Steps

In the same manner as in Reference Example 5, starting from 1.38 g of (1S)-1-[(2R)-2-(2,4-difluorophenyl)-2-oxiranyl]ethanol and 1.09 g of 1-(4-chlorophenyl)-5(1H,4H)-tetrazolone, 1.27 g of 1-(4-chlorophenyl)-4-[(1R,2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-5(1H,4H)-tetrazolone was obtained as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05371101
Source datasetuspto-grants-1994_12
ORD IDord-964a29a06fea436f8f81995e80bb880f
Source noteuspto-grants-1994_12