Ammonia → HCID 18953789, compound

HRID 1491819Notes

Reaction equation

HRID 1491819 reaction equation
C([O:3][C:4]([C:6]1[S:7][CH:8]=[C:9]([C:11](=[O:13])[CH3:12])[N:10]=1)=O)C.[NH3:14]>>[C:11]([C:9]1[N:10]=[C:6]([C:4]([NH2:14])=[O:3])[S:7][CH:8]=1)(=[O:13])[CH3:12]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 12362482HCID 12362482, compound

Product 1

HCID 18953789HCID 18953789, compound

Procedure

A suspension of 4-acetyl-2-thiazolecarboxylic acid ethyl ester (2.5 g) in 28% aqueous ammonia solution (40 ml) was stirred for 1 hour at room temperature. The resulting precipitate was collected by filtration to afford 4-acetyl-2-thiazolecarboxamide (1.76 g).

Workup

  1. filtrationThe resulting precipitate was collected by filtration

Sources & evidence

ORD record
ord-68c5803b6fae4a4abdd4dd7926b2fb39
Source dataset
uspto-grants-1994_12
Patent number
US05371097

Reaction notes

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