HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Iodide → 3-[4-[1-(3-Chlorophenyl)-4-piperazinyl]butyl]-2-Methyl-4-thiazolidinone hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Iodide | HCID 5238 | — |
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | 1-(3-Chlorophenyl)piperazine monohydrochloride | HCID 25681 | — |
| Edukt | 3-(4-Bromobutyl)-2-methyl-4-thiazolidinone | HCID 10490993 | — |
| Lösungsmittel | Acetonitrile | HCID 6342 | — |
| Produkt | 3-[4-[1-(3-Chlorophenyl)-4-piperazinyl]butyl]-2-Methyl-4-thiazolidinone hydrochloride | HCID 14856141 | — |
Reaktionsschritte
To a solution of 2-methyl-3-(4-bromobutyl)-4-thiazolidinone (4.0 g) and 1-(3-chlorophenyl)piperazine hydrochloride (3.69 g) in 100 ml of dry CH3CN were added K2CO3 (8.8 g) and NaI (200 mg). The mixture was heated to reflux with stirring under N2.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05371087 |
| Quelldatensatz | uspto-grants-1994_12 |
| ORD ID | ord-70e348c5ae3448c1bf9a7efa1973c8d8 |
| Quellennotiz | uspto-grants-1994_12 |