HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dodecanoyl chloride → 2,6-Diphenyl-3,5-dimethylpiperidin-4-yl Laurate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dodecanoyl chloride | HCID 8166 | — |
| Reactant | 3,5-Dimethyl-2,6-diphenylpiperidin-4-ol | HCID 338206 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | 2,6-Diphenyl-3,5-dimethylpiperidin-4-yl Laurate | HCID 53685275 | 74.4% |
Reaction Steps
The general procedure of Example 1 is repeated using 28.1 g (0.10 mol) of 2,6-diphenyl-3,5-dimethyl-4-hydroxypiperidine, 40 mL (0.10 mol) of n-butyllithium (2.5M in hexanes) and 21.8 g (0.10 mol) of lauroyl chloride. 34.5 g (74% yield) of the title compound is isolated after purification by LC (silica gel, ethyl acetate/hexane): mp 74°-76° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05371125 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-84db298bef194a7e9d32317fcf4cf390 |
| Source note | uspto-grants-1994_12 |