HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → Benzyl Phenyl Ether
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Sodium amide | HCID 24533 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Barium Oxide Nanoparticle Dispersion | HCID 9855530 | — |
| Catalyst | Silver(II) oxide | HCID 92152 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | Benzyl Phenyl Ether | HCID 70352 | — |
Reaction Steps
In Scheme 3, the starting phenol is reacted with a benzyl halide in the presence of a base (e.g. sodium amide, triethylamine, sodium hydroxide, barium oxide, silver oxide, sodium hydride) in an inert solvent (e.g. ether, dimethylsulfoxide, dimethylformamide, tetrahydrofuran) to give a benzyl phenyl ether, which is an example of the derivative of the alkoxyiminocarboxylic acid (V).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05371222 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-ca0bee91e9eb4d229b374d2ca0884965 |
| Source note | uspto-grants-1994_12 |