Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-bromobutanimide → (E)-Methyl 2-(methoxyimino)-2-[2-(bromomethyl)phenyl]acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | Methyl (2E)-(methoxyimino)(2-methylphenyl)acetate | HCID 10998216 | — |
| 촉매 | Benzoyl Peroxide | HCID 7187 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | (E)-Methyl 2-(methoxyimino)-2-[2-(bromomethyl)phenyl]acetate | HCID 10989774 | 106.7% |
반응 단계
Methyl-(E)-2-(2-tolyl)-2-methoxyiminoacetate (4.74 g) was dissolved in carbon tetrachloride (100 ml), and N-bromosuccinimide (4.89 g) and benzoylperoxide (554 mg) were added thereto. The resultant mixture was heated under reflux for 1 hour and cooled to room temperature. Insoluble materials were removed by filtration. On concentration of the solvent, the residue was purified by silica gel column chromatography with a mixture of hexane and ethyl acetate to give methyl-(E)-2-(2-bromomethylphenyl)-2-methoxyiminoacetate (6.98 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05371222 |
| 출처 데이터셋 | uspto-grants-1994_12 |
| ORD ID | ord-b7e5a53db21f46db8890ab0fa1214e58 |
| 출처 메모 | uspto-grants-1994_12 |