HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-Benzyloxypropyl)-3-hydroxy-gamma-butyrolactone → 2-(3-Hydroxypropyl)-3-hydroxy-gamma-butyrolactone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-Benzyloxypropyl)-3-hydroxy-gamma-butyrolactone | HCID 18953752 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Acetic acid ethanol | HCID 18476134 | — |
| Product | 2-(3-Hydroxypropyl)-3-hydroxy-gamma-butyrolactone | HCID 18953769 | — |
Reaction Steps
A solution of 18.7 g of 2-(3-benzyloxypropyl)-3-hydroxy-γ-butyrolactone in 90 ml of ethanol-acetic acid (2:1) is hydrogenated over 640 mg of 10% palladium on carbon at 45 psi for 20 h. The catalyst is filtered and the filtrates are evaporated to give 2-(3-hydroxypropyl)-3-hydroxy-γ-butyrolactone as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05371096 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-010b69b71e544316854b40939d0eaf01 |
| Source note | uspto-grants-1994_12 |