HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18657616, compound → HCID 44305824, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18657616 | HCID 18657616 | — |
| Reactant | HCID 67797893 | HCID 67797893 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 44305824 | HCID 44305824 | — |
Reaction Steps
(Z)-(2R,3R,4S)-7-[4-(biphenyl-4-ylmethoxy)-2-(3-pyridyl)tetrahydrofuran-3-yl]hept-4-enoic acid having mp 94°-96° C. and [α]D25 =-83.75° (MeOH) is prepared from (2R,3R,4S)-3-(3-t-butyldimethylsilyloxypropan-1-yl)-4-[(R)-(-)-α-methoxyphenylacetoxy]-2-(3-pyridyl)tetrahydrofuran as described for the synthesis of (Z)-(2S,3S,4R)-7-[4-(biphenyl-4-ylmethoxy)-2-(3-pyridyl)tetrahydrofuran-3-yl]hept-4-enoic acid in example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05371096 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-c9963b0a3fb64407a54ea0ac242228f4 |
| Source note | uspto-grants-1994_12 |