Ethanol → HCID 67823864, compound

Participants

Reaction Steps

A method similar to Example 1 was used and 12.8 g (65 mmol) of 1-(2,6-difluorophenyl)-cyclopropanecarboxylic acid, dissolved in 60 ml of ethanol, were converted with 4.0 g (71 mmol) of potassium hydroxide into the potassium salt of 2,6-difluorophenylcyclopropanecarboxylic acid, and said salt was then reacted, at 100° C., in 100 ml of N-methylpyrrolidone, with 11.4 g (40 mmol) of methyl alpha-(2-bromomethylphenyl)-betamethoxyacrylate. The resulting oily product was covered with a layer of diisopropyl ether and was crystallized by rubbing the wall of the vessel. Yield: 86%; mp.: 108°-110° C.; white crystals.

Provenance & Evidence