4-Acetylamino-2-chlorophenol → N-(4-hydroxy-3-chloro-1-naphthyl)-2-aminoacetamide

HRID 1492122Notes

Reaction equation

HRID 1492122 reaction equation
Cl[C:2]1[CH:3]=[C:4]([CH:9]=[C:10]([Cl:13])[C:11]=1[OH:12])[NH:5][C:6](=[O:8])[CH3:7].Cl[C:15]1[CH:16]=C(C=[CH:23][C:24]=1O)NC(=O)C.ClC1C(C)=C(C=C(Cl)C=1O)[NH:30]C(=O)C>>[OH:12][C:11]1[C:2]2[C:3](=[CH:16][CH:15]=[CH:24][CH:23]=2)[C:4]([NH:5][C:6](=[O:8])[CH2:7][NH2:30])=[CH:9][C:10]=1[Cl:13]

Participants

4

Reactant 3

HCID 775794-Acetylamino-2-chlorophenolHCID 100821803',5'-Dichloro-4'-hydroxyacetanilideHCID 189519353',5'-Dichloro-4'-hydroxy-2'-methylacetanilide

Product 1

HCID 18931976N-(4-hydroxy-3-chloro-1-naphthyl)-2-aminoacetamide

Procedure

The preferred peroxidase stabilizers are 3',5'-dichloro-4'-hydroxyacetanilide, 3'-chloro-4'-hydroxyacetanilide and 3',5'-dichloro-4'-hydroxy-2'-methylacetanilide.

Sources & evidence

ORD record
ord-bf3e5dd7315445dd8f06128bed672b3e
Source dataset
uspto-grants-1994_12
Patent number
US05372932

Reaction notes

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