Aniline → 3-Methyl-N-phenylbut-2-enamide

HRID 1492166Notes

Reaction equation

[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:8][C:9]([CH3:14])=[CH:10][C:11](Cl)=[O:12]>>[C:2]1([NH:1][C:11](=[O:12])[CH:10]=[C:9]([CH3:14])[CH3:8])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 6115Aniline

HCID 1023943-Methyl-2-butenoyl chloride

Product 1

HCID 123870223-Methyl-N-phenylbut-2-enamideYield 86%

Procedure

This is prepared analogously to a) from aniline and 3,3-dimethylacryloyl chloride. Yield 86% of theory; m.p. 124°-126° C.

Sources & evidence

ORD record: ord-db2247c9a9b74e858a628933ccf9b5fa
Source dataset: uspto-grants-1994_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05373019

Reaction notes

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