HCID 15746377, compound → HCID 67849111, compound

HRID 1492210Notes

Reaction equation

HRID 1492210 reaction equation
[CH3:1][N:2]1[CH2:6][CH2:5][N:4]([CH3:7])[C:3]1=[N:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[N:15]1[CH2:20][CH2:19][S:18][CH2:17][CH2:16]1.I([O-])(=O)(=O)=[O:22].[Na+]>CO.O>[OH2:22].[CH3:1][N:2]1[CH2:6][CH2:5][N:4]([CH3:7])[C:3]1=[N:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[N:15]1[CH2:16][CH2:17][S:18](=[O:22])[CH2:19][CH2:20]1

Participants

5

Reactant 2

HCID 15746377HCID 15746377, compoundHCID 23667635Sodium periodate

Product 1

HCID 67849111HCID 67849111, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

Reaction of 4-[2-(1,3-dimethyl-2-imidazolidinylideneamino)phenyl]thiamorpholine (1.5 g prepared as described in Example 144) in methanol (20 ml) and sodium metaperiodate (1.4 g) in water (4 ml) for 4 hours at 10° C. yielded 4-[2-(1,3-dimethyl-2-imidazolidinylideneamino)phenyl]thiamorpholine-1-oxide monohydrate (m.p. 103°-105° C.) which was recrystallised from a 1:1 mixture of 1,2-dimethoxyethane and hexane.

Sources & evidence

ORD record
ord-82e414a40eec4dd0bd7b2455ea069e41
Source dataset
uspto-grants-1994_12
Patent number
US05373008

Reaction notes

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