Thiophosgene → HCID 18952334, compound

HRID 1492213Notes

Reaction equation

HRID 1492213 reaction equation
[CH3:1][C:2]1[C:7]([NH2:8])=[C:6]([N:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)[CH:5]=[CH:4][CH:3]=1.[C:15](Cl)(Cl)=[S:16]>O1CCOCC1.O>[CH3:1][C:2]1[C:7]([N:8]=[C:15]=[S:16])=[C:6]([N:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)[CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 2

HCID 10040ThiophosgeneHCID 18952122HCID 18952122, compound

Product 1

HCID 18952334HCID 18952334, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 312751,4-DioxaneSolvent

Procedure

Reaction of 6-methyl-2-morpholinoaniline (9.6 g) in dioxan (25 ml) and water (100 ml) with thiophosgene (5.7 ml) at 0° C. for 30 minutes and at room temperature for 3 hours gave 6-methyl-2-morpholinophenyl isothiocyanate as an oil.

Sources & evidence

ORD record
ord-ee0aaa6b84444c189c2745db36f27940
Source dataset
uspto-grants-1994_12
Patent number
US05373008

Reaction notes

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