Ammonia → HCID 18952310, compound

HRID 1492227Notes

Reaction equation

HRID 1492227 reaction equation
[CH3:1][C:2]1[C:7]([N:8]=[C:9]=[S:10])=[C:6]([N:11]2[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]2)[CH:5]=[CH:4][CH:3]=1.[NH3:17]>C(O)C>[CH3:1][C:2]1[C:7]([NH:8][C:9]([NH2:17])=[S:10])=[C:6]([N:11]2[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]2)[CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 18952326HCID 18952326, compound

Product 1

HCID 18952310HCID 18952310, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Reaction of 6-methyl-2-piperidinophenyl isothiocyanate (6.8 g) with 25% aqueous ammonia solution (65 ml) in ethanol (20 ml) for 8 hours at room temperature gave 1-(6-methyl-2-piperidinophenyl) thiourea as a pale yellow solid (m.p. 197°-198° C.).

Sources & evidence

ORD record
ord-843c4be5a7204b96a0c887c213a810eb
Source dataset
uspto-grants-1994_12
Patent number
US05373008

Reaction notes

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