Methyl iodide → HCID 18952330, compound

HRID 1492238Notes

Reaction equation

HRID 1492238 reaction equation
[CH2:1]([NH:3][C:4]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[N:13]1[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1)=[S:5])[CH3:2].[CH3:19][I:20]>CC(C)=O>[IH:20].[CH3:19][S:5][C:4](=[N:3][CH2:1][CH3:2])[NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[N:13]1[CH2:14][CH2:15][O:16][CH2:17][CH2:18]1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 8625259HCID 8625259, compound

Product 1

HCID 18952330HCID 18952330, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of 1-ethyl-3-(2-morpholinophenyl) thiourea (3.2 g) and methyliodide (2 g) in acetone (25 ml) was heated at reflux for 4 hours to yield 2-methyl-3-ethyl-1-(2-morpholinophenyl)-2-thiopseudourea hydroiodide as a pale yellow solid (m.p. 170°-172° C.) which was recrystallised from acetone.

Workup

  1. temperaturewas heated
  2. temperatureat reflux for 4 hours

Sources & evidence

ORD record
ord-eae49d7ed0ca409c9f93cdd9fd80bc9d
Source dataset
uspto-grants-1994_12
Patent number
US05373008

Reaction notes

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