Ammonia → HCID 18952331, compound

HRID 1492271Notes

Reaction equation

HRID 1492271 reaction equation
[C:1]([C:3]1[CH:4]=[CH:5][C:6]([N:12]2[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)=[C:7]([N:9]=[C:10]=[S:11])[CH:8]=1)#[N:2].[NH3:18]>C(O)C>[C:1]([C:3]1[CH:4]=[CH:5][C:6]([N:12]2[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)=[C:7]([NH:9][C:10]([NH2:18])=[S:11])[CH:8]=1)#[N:2]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 189521945-Cyano-2-morpholinophenyl isothiocyanate

Product 1

HCID 18952331HCID 18952331, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Reaction of 5-cyano-2-morpholinophenyl isothiocyanate (2.5 g) in ethanol (10 ml) with 25% aqueous ammonia solution (1 ml) at room temperature for 3 hours gave 1-(5-cyano-2-morpholinophenyl)thiourea (m.p. 193°-194° C.).

Sources & evidence

ORD record
ord-064ba75f44dd4be099dfb2b5462beca7
Source dataset
uspto-grants-1994_12
Patent number
US05373008

Reaction notes

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