Ammonia → HCID 18952303, compound

HRID 1492284Notes

Reaction equation

HRID 1492284 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]([N:11]2[CH2:16][CH2:15][O:14][CH2:13][CH2:12]2)=[C:6]([N:8]=[C:9]=[S:10])[CH:7]=1.[NH3:17]>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([N:11]2[CH2:16][CH2:15][O:14][CH2:13][CH2:12]2)=[C:6]([NH:8][C:9]([NH2:17])=[S:10])[CH:7]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 18952176HCID 18952176, compound

Product 1

HCID 18952303HCID 18952303, compound

Procedure

Reaction of 5-fluoro-2-morpholinophenyl isothiocyanate (5.8 g) with 33% ethanolic ammonia solution (30 ml) at room temperature for 3 hours gave 1-(5-fluoro-2-morpholinophenyl)thiourea as a white solid (m.p. 195-196).

Sources & evidence

ORD record
ord-02a40edf9c75416ab7ba875b4d6939aa
Source dataset
uspto-grants-1994_12
Patent number
US05373008

Reaction notes

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