HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dimethyl-2-imidazolidinone → 4-[2-(1,3-Dimethyl-2-imidazolidinylideneamino)benzyl]morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dimethyl-2-imidazolidinone | HCID 6661 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 2-(Morpholin-4-ylmethyl)aniline | HCID 6484555 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 4-[2-(1,3-Dimethyl-2-imidazolidinylideneamino)benzyl]morpholine | HCID 15746371 | — |
Reaction Steps
A mixture of 1,3-dimethyl-2-imidazolidinone (4.6 g) in benzene (40 ml), 4-(2-aminobenzyl)morpholine (3.8 g) in benzene (20 ml) and phosphorus oxychloride (3.6 ml) was heated at 65°-70° C. for 20 hours to yield 4-[2-(1,3-dimethyl-2-imidazolidinylideneamino)benzyl]morpholine (m.p. 56°-58° C.) which was recrystallised from hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05373008 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-2386c9ed13bd48c582e1424c4a163b4f |
| Source note | uspto-grants-1994_12 |