Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
M-Cresol → HCID 178511983, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | M-Cresol | HCID 342 | — |
| 반응물 | 4-Morpholinecarbonitrile | HCID 73738 | — |
| 반응물 | 4-(2-Aminobenzyl)morpholine dihydrochloride | HCID 18952228 | — |
| 생성물 | HCID 178511983 | HCID 178511983 | — |
반응 단계
A mixture of 4-(2-aminobenzyl)morpholine dihydrochloride (6.8 g), 4-cyanomorpholine (4.3 g) and m-cresol was heated at 90°-95° C. for 12 hours to yield N-(2-morpholinomethylphenyl)morpholine-4-carboxamidine (m.p. 118°-119° C.) which was recrystallised from hexane and then converted into its difumarate salt (m.p. 166°-167° C.) which was recrystallised from propan-2-ol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05373008 |
| 출처 데이터셋 | uspto-grants-1994_12 |
| ORD ID | ord-901a538294e845b3a3b6f0e61f4d9f6e |
| 출처 메모 | uspto-grants-1994_12 |