HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Alcohol → 2,6-bis(benzyloxy)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Alcohol | HCID 244 | — |
| Reactant | 2,6-Dichloropyridine | HCID 16989 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2,6-bis(benzyloxy)pyridine | HCID 819936 | — |
Reaction Steps
Benzyl alcohol (5.1 g; 0.05 mols) was reacted with 2,6-dichloropyridine (3.5 g; 0.024 mols) utilizing sodium hydride (1.2 g) and, as solvent, dimethylformamide by the procedure of Example 1 above. Usual work up, chromatography and recrystallisation gave 2,6-dibenzyloxypyridine as a colorless solid (5.5 g; 81%). Melting point: 74° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05374604 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-f9b3b78878424aa0a87f6d1f1d47ea93 |
| Source note | uspto-grants-1994_12 |