Ethyl orthoformate → HCID 54397850, compound

HRID 1492383Notes

Reaction equation

HRID 1492383 reaction equation
[CH3:1][S:2][C:3]1[C:8]([CH2:9][S:10][CH3:11])=[C:7]([Cl:12])[CH:6]=[CH:5][C:4]=1[C:13](=[O:20])[CH2:14][C:15]([CH:17]1[CH2:19][CH2:18]1)=[O:16].[CH2:21]([O:23][CH:24](OCC)OCC)[CH3:22]>C(OC(=O)C)(=O)C>[CH3:1][S:2][C:3]1[C:8]([CH2:9][S:10][CH3:11])=[C:7]([Cl:12])[CH:6]=[CH:5][C:4]=1[C:13](=[O:20])[C:14](=[CH:24][O:23][CH2:21][CH3:22])[C:15]([CH:17]1[CH2:18][CH2:19]1)=[O:16]

Participants

4

Reactant 2

HCID 31214Ethyl orthoformateHCID 18950268HCID 18950268, compound

Product 1

HCID 54397850HCID 54397850, compound

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

A mixture of 1-[2-(methylsulphenyl)-3-(methylsulphenylmethyl)-4-chlorophenyl]-3-cyclopropylpropan-1,3-dione (1.5 g) and triethylorthoformate (8 ml) in acetic anhydride (25 ml) was heated at reflux temperature for 4 hours. The excess reagent and solvent were evaporated under reduced pressure, yielding 1-[2-(methylsulphenyl)-3-(methylsulphenylmethyl)-4-chlorophenyl]-2-ethoxymethylene-3-cyclopropylpropan-1,3-dione as a brown oil (2.3 g).

Workup

  1. temperaturewas heated
  2. temperatureat reflux temperature for 4 hours
  3. customThe excess reagent and solvent were evaporated under reduced pressure

Sources & evidence

ORD record
ord-0875ef0d642045059ee125acb66af82d
Source dataset
uspto-grants-1994_12
Patent number
US05374606

Reaction notes

Loading…