Ethanol → HCID 21740545, compound

Participants

Reaction Steps

Ethyl 4-[2-benzenesulfonamido-2-(3-pyridyl)ethyl]phenoxyacetate (70 mg) was dissolved in 2 ml of ethanol and 2 ml of tetrahydrofuran, followed by addition of 0.30 ml of aqueous 2N sodium hydroxide solution, and stirred at room temperature for one hour. The solvent was concentrated under reduced pressure, and neutralized with 2N hydrogen chloride. Then, the crystalline deposited was taken out by filtration and recrystallized in aqueous ethanol, to yield 15 mg of ethyl 4-[2-benzenesulfonamido-2-(3-pyridyl)ethyl]phenoxyacetic acid. The spectrometric data thereof supports the structure of [21] as follows.

Provenance & Evidence