反应详情

Methyl p-tolylacetate (11 g) was dissolved in 250 ml of carbon tetrachloride, followed by addition of 11.7 g of N-bromosuccinimide and 0.15 g of benzoyl peroxide, and refluxed under heating for 2.5 hours. The reaction mixture obtained was cooled, followed by filtration and distillation of the solvent, which was then fractionated at 4 mmHg and 142 to 150 ° C. to produce methyl 4-bromomethylphenylacetate (5.3 g).

1. temperaturerefluxed
2. temperatureunder heating for 2.5 hours
3. customThe reaction mixture obtained
4. temperaturewas cooled
5. filtrationfollowed by filtration and distillation of the solvent, which
6. customwas then fractionated at 4 mmHg and 142 to 150 ° C.