Azobisisobutyronitrile → HCID 19385691, compound

Participants

Reaction Steps

To a solution of 0.780 g (2.21 mmol) of the product of Step A dissolved in 12 mL of CCl4 was added 0.394 g (2.21 mmol) of N-bromosuccinimide and 20 mg (catalytic amount) of AIBN. The mixture was stirred and refluxed under a N2 atmosphere for 6 hours. The mixture was then cooled, filtered and evaporated in vacuo. The residue was purified on a silica gel flash chromatography column eluted with 7% ethyl acetate/hexane to afford 0.203 g (21%) of the title compound.

Provenance & Evidence