Trifluoroacetic acid → HCID 19385602, compound

Participants

Reaction Steps

To a solution of 3-[4-(1-carbo-t-butoxy-1-phenylmethoxy)-3propylphenylmethyl]-5-carboxy-2-ethyl-7-methyl-3H-imidazo[4,5-b]pyridine (47 mg, 0.087 mmol) in CHCl3 (3 mL) was added TFA (0.5 mL) at -20° C. The solution was warmed to rt and was stirred at rt for 12 hours. After evaporation of the solvent the crude mixture was purified by flash chromatography eluted with CHCl3 /MeOH/AcOH (90:5:5) to give 31 mg of the title compound as a white solid.

Provenance & Evidence