Sulfuric Acid → HCID 14597127, compound

HRID 1492688Notes

Reaction equation

HRID 1492688 reaction equation
[OH:1][C:2]1[CH:14]=[CH:13][C:5]2[O:6][C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=3[C:4]=2[CH:3]=1.[N:15]([O-])=[O:16].[Na+].S(=O)(=O)(O)O>N1C=CC=CC=1>[N:15]([C:3]1[C:4]2[C:8]3[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=3[O:6][C:5]=2[CH:13]=[CH:14][C:2]=1[OH:1])=[O:16]

Participants

5

Reactant 3

HCID 1118Sulfuric AcidHCID 665872-DibenzofuranolHCID 23668193Sodium Nitrite

Product 1

HCID 14597127HCID 14597127, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Conditions

Temperature
0 °C

Procedure

In 100 g of pyridine was dissolved 10 g of 2-hydroxydibenzofuran, and the solution was cooled to 0° C. Then, 60 g of a 20% aqueous solution of sodium nitrite was added to the above solution and 100 g of a 30% aqueous solution of sulfuric acid was added dropwise to the mixture while stirring for 10 minutes. After the dropwise addition, the mixture was stirred at 0° C. for 1 hour and then filtered. The recovered solid was washed with water and dried to obtain 11 g of a red crystal of 1-nitroso-2-hydroxydibenzofuran.

Workup

  1. additionwas added dropwise to the mixture
  2. additionAfter the dropwise addition
  3. stirringthe mixture was stirred at 0° C. for 1 hour
  4. filtrationfiltered
  5. washThe recovered solid was washed with water
  6. customdried

Sources & evidence

ORD record
ord-b2afefacf3df4198ae6ae09e57a96050
Source dataset
uspto-grants-1994_12
Patent number
US05374723

Reaction notes

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