反应详情

To a suspension of 2-butyl-1H-imidazole-5-methanol (2.02 g) in dry dichloromethane (40 ml) and dry dioxan (60 ml) was added manganese dioxide (7.05 g). The reaction mixture was heated at reflux for 3.5 h before being filtered, and the filtrate concentrated in vacuo to give the title compound as a white solid (1.69 g).

1. temperatureThe reaction mixture was heated
2. temperatureat reflux for 3.5 h
3. filtrationbefore being filtered
4. concentrationthe filtrate concentrated in vacuo